Follicular Lymphoma

Follicular Lymphoma Epidemiology

  • An estimated 1 in 5 lymphomas diagnosed in the United States are FL1
  • FL is the most common indolent lymphoma, and 2nd most common non-Hodgkin’s Lymphoma accounts for 10-20% of all lymphomas in Western Countries3
    • FL is indolent (slow growing), though in some cases it can grow quickly1
  • The average age at diagnosis is 60 years, though the incidence increases from 30-70 years old1,2
  • FL responds to treatment, but is hard to cure with frequent relapses and shorter duration of response1,3
    • Approximately 3% of FL patients progress to an aggressive disease that resembles large B-cell lymphoma which severely worsens outcomes and 10-year survival drops from 75% to 36% in patients with transformed lymphoma3
    • There is a slight preponderance in women3
  • Many patients with FL have widespread disease at diagnosis, bone marrow involvement is common and is present in > 50% of patients3



  1. American Cancer Society. Types of Non-Hodgkin Lymphoma. Available: Accessed: May, 2018
  2. Teras LR, DeSantis CE, Cerhan JR, et al. U.S. Lymphoid Malignancy Statistics by World Health Organization. CA: A Cancer Journal for Clinicians. 2016. Vol 66, Iss 6, pp 443-459
  3. Union for International Cancer Control. “Follicular Lymphoma” 2014 Review of Cancer Medications on the WHO List of Essential Medicines. Available: Accessed: June, 2018