Follicular Lymphoma
Follicular Lymphoma Epidemiology
- An estimated 1 in 5 lymphomas diagnosed in the United States are FL1
- FL is the most common indolent lymphoma, and 2nd most common non-Hodgkin’s Lymphoma accounts for 10-20% of all lymphomas in Western Countries3
- FL is indolent (slow growing), though in some cases it can grow quickly1
- The average age at diagnosis is 60 years, though the incidence increases from 30-70 years old1,2
- FL responds to treatment, but is hard to cure with frequent relapses and shorter duration of response1,3
- Approximately 3% of FL patients progress to an aggressive disease that resembles large B-cell lymphoma which severely worsens outcomes and 10-year survival drops from 75% to 36% in patients with transformed lymphoma3
- There is a slight preponderance in women3
- Many patients with FL have widespread disease at diagnosis, bone marrow involvement is common and is present in > 50% of patients3
References:
- American Cancer Society. Types of Non-Hodgkin Lymphoma. Available: www.cancer.org/cancer/non-hodgkin-lymphoma/about/types-of-non-hodgkin-lymphoma.html. Accessed: May, 2018
- Teras LR, DeSantis CE, Cerhan JR, et al. U.S. Lymphoid Malignancy Statistics by World Health Organization. CA: A Cancer Journal for Clinicians. 2016. Vol 66, Iss 6, pp 443-459
- Union for International Cancer Control. “Follicular Lymphoma” 2014 Review of Cancer Medications on the WHO List of Essential Medicines. Available: www.who.int/selection_medicines/committees/expert/20/applications/FollicularLymphoma.pdf. Accessed: June, 2018